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We dont have large randomized trials that look at long term safety, live birth, and health of offspring

Most methylated B complex formulas omit NAC limiting this pathway entirely

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Pilot clinical studies and case reports describe nausea in 65% of subjects at doses above 0,5 mg (resolution 2-4 h post-injection), flushing in 55%, transient increases in blood pressure and tachycardia in 40-60% of subjects, with peak acute effects occurring 90-120 minutes post-dose

Hair regrowth typically begins within three to six months of the shedding phase peaking